Aspergillus sclerotioniger CBS115572 v1.0
Aspergillus sclerotioniger
Photo credit: Ellen Kirstine Lyhne

This species was sequenced as a part of the Aspergillus whole-genus sequencing project - a project dedicated to performing whole-genome sequencing of all members of the Aspergillus genus. The Aspergilli is a ubiquitous and species-rich genus, currently containing more than 300 filamentous fungi. The genus covers a wide range of phenotypes and has a substantial economic foot print, as it includes fermenters of foodstuffs, key cell factories for production of enzymes and organic acids, plant pathogens, model organisms for cell biology, human opportunistic pathogens, producers of animal and human mycotoxins, and degraders of a wide range of organic biomass relevant for bioenergy conversion.

Aspergillus sclerotioniger (MB 500010)

A. sclerotioniger Frisvad & Samson was described in Stud Mycol 50: 45-61, 2004 (on page 57). This species is placed in the A. carbonarius clade (Varga et al., Stud Mycol 69: 1-17, 2011). It has been found in a green coffee bean, Karnataka, India. It is a very effective producer of ochratoxin A (OTA), ochratoxin B, and also produces aurasperone B, pyranonigrin A, corymbiferan lactone-like exometabolites and some cytochalasins. Sclerotia are produced on all media at the expense of conidial structures. Predominantly sclerotium associated exometabolites include ochratoxin A, but no indoloterpenes have been found in the sclerotia. Bioindustrial application will require that the OTA gene cluster is silenced or one of the genes in the pathway for OTA is inactivated.