Annotations/Genomes | Total | Annotation Description | ||||||
---|---|---|---|---|---|---|---|---|
Merops | 326 | 273 | 379 | 401 | 436 | 248 | 2,063 | |
19 | 10 | 20 | 20 | 20 | 14 | 103 | Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms | |
7 | 8 | 8 | 11 | 10 | 3 | 47 | Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane. | |
26 | 27 | 33 | 28 | 28 | 26 | 168 | Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence | |
4 | 3 | 3 | 3 | 4 | 3 | 20 | Cysteine nucleophile; catalytic residues in the order His, Cys in sequence | |
1 | 2 | 3 | 2 | 1 | 1 | 10 | Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence | |
1 | 2 | 2 | 2 | 2 | 1 | 10 | Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence | |
1 | 1 | 1 | 1 | 4 | Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence | |||
1 | 1 | 1 | 1 | 1 | 1 | 6 | Cysteine nucleophile; catalytic residues in the order His, Cys in sequence | |
2 | 3 | 5 | 1 | 1 | 12 | Water nucleophile; water bound by Gln and Glu; all endopeptidases | ||
4 | 6 | 6 | 5 | 5 | 4 | 30 | Families of peptidase inhibitors not assigned to clans | |
2 | 1 | 1 | 1 | 1 | 1 | 7 | ||
7 | 4 | 5 | 3 | 4 | 3 | 26 | ||
4 | 5 | 7 | 6 | 3 | 4 | 29 | Families of metallopeptidases not assigned to clans | |
16 | 8 | 14 | 17 | 22 | 10 | 87 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp | |
5 | 4 | 3 | 2 | 5 | 4 | 23 | Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His | |
1 | 1 | 2 | 2 | 2 | 2 | 10 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu | |
7 | 6 | 10 | 10 | 7 | 7 | 47 | Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu | |
24 | 22 | 28 | 28 | 26 | 19 | 147 | Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His | |
10 | 8 | 18 | 14 | 15 | 7 | 72 | Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His. | |
2 | 3 | 3 | 3 | 3 | 3 | 17 | Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D) | |
1 | 1 | Water nucleophile; water bound by single zinc ion ligated to Asp, His and His. | ||||||
2 | 2 | 1 | 3 | 1 | 9 | Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases | ||
21 | 21 | 21 | 22 | 23 | 21 | 129 | Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme | |
6 | 5 | 4 | 6 | 10 | 7 | 38 | Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence. | |
1 | 1 | 1 | 3 | Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His | ||||
1 | 1 | 1 | 1 | 1 | 5 | Serine or threonine nucleophile; N-terminal nucleophile | ||
7 | 8 | 7 | 12 | 12 | 8 | 54 | Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs | |
117 | 88 | 143 | 146 | 183 | 72 | 749 | Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence | |
4 | 2 | 6 | 12 | 17 | 2 | 43 | Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence | |
3 | 3 | 3 | 3 | 3 | 4 | 19 | Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence | |
2 | 2 | 2 | 3 | 1 | 1 | 11 | Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence | |
1 | 1 | Serine nucleophile; catalytic residues in the order Ser, Glu, His | ||||||
3 | 5 | 2 | 3 | 5 | 3 | 21 | Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane | |
1 | 1 | 1 | 3 | |||||
13 | 14 | 14 | 20 | 12 | 12 | 85 | ||
1 | 1 | 1 | 3 | |||||
1 | 1 | 2 | ||||||
2 | 1 | 2 | 3 | 3 | 1 | 12 |