Annotations/Genomes | Total | Annotation Description | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Merops | 287 | 315 | 196 | 362 | 148 | 1,308 | |||||
11 | 36 | 20 | 81 | 8 | 156 | Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms | |||||
1 | 10 | 11 | Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane. | ||||||||
1 | 2 | 1 | 1 | 5 | Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane. | ||||||
5 | 1 | 6 | Water nucleophile; water bound by two Asp | ||||||||
15 | 20 | 8 | 19 | 18 | 80 | Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence | |||||
5 | 6 | 6 | 4 | 2 | 23 | Cysteine nucleophile; catalytic residues in the order His, Cys in sequence | |||||
1 | 1 | 1 | 2 | 1 | 6 | Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence | |||||
1 | 1 | Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence | |||||||||
1 | 1 | Water nucleophile; water bound by Gln and Glu; all endopeptidases | |||||||||
7 | 3 | 2 | 2 | 2 | 16 | Families of peptidase inhibitors not assigned to clans | |||||
1 | 1 | 2 | |||||||||
1 | 1 | 2 | 4 | ||||||||
5 | 2 | 2 | 1 | 10 | |||||||
3 | 3 | 4 | 2 | 2 | 14 | Families of metallopeptidases not assigned to clans | |||||
30 | 15 | 11 | 15 | 7 | 78 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp | |||||
1 | 1 | 2 | Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His | ||||||||
1 | 1 | 1 | 1 | 4 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu | ||||||
1 | 1 | 1 | 3 | Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu | |||||||
7 | 9 | 4 | 8 | 4 | 32 | Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu | |||||
22 | 16 | 3 | 15 | 6 | 62 | Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His | |||||
8 | 11 | 8 | 17 | 4 | 48 | Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His. | |||||
1 | 1 | 2 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site. | ||||||||
1 | 1 | 2 | Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH) | ||||||||
7 | 6 | 1 | 5 | 5 | 24 | Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D) | |||||
1 | 1 | 2 | Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases | ||||||||
1 | 2 | 3 | Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases | ||||||||
19 | 22 | 8 | 20 | 18 | 87 | Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme | |||||
8 | 6 | 3 | 4 | 1 | 22 | Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence. | |||||
8 | 11 | 10 | 9 | 2 | 40 | Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs | |||||
99 | 112 | 75 | 101 | 50 | 437 | Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence | |||||
2 | 4 | 5 | 4 | 3 | 18 | Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence | |||||
2 | 3 | 6 | 3 | 1 | 15 | Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence | |||||
1 | 1 | 1 | 1 | 4 | Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence | ||||||
3 | 3 | 4 | 5 | 15 | Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane | ||||||
1 | 1 | Families of peptidases of unknown catalytic mechanism not assigned to clans | |||||||||
1 | 1 | 1 | 1 | 4 | |||||||
10 | 14 | 11 | 20 | 6 | 61 | ||||||
1 | 1 | ||||||||||
3 | 1 | 2 | 6 |