Peptidases • Parasitella parasitica v1.0
Annotations/GenomesBacci1Lichy1Mucci2Parpar1Phybl2Rhimi1_1Umbra1TotalAnnotation Description
Merops
4223113042652842532722,111
31252419282022169Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1034344331Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
40353530292924222Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
656576237Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1612232228Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1211128Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
221121110Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
977767649Families of peptidase inhibitors not assigned to clans
11
11114
112
11
2125
11111218
532311116
11111117Families of metallopeptidases not assigned to clans
26162320171822142Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
3115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
454434327Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1511131212141188Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1617111015111797Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
117127961062Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1121117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
736556234Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
321311314Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
35202321171718151Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
453333324Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
2215101119111098Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
96826761554671478Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1311118Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
745746336Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
33Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
213131213Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1167476445Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
21111118
26232420262417160
1113
11
11