Peptidases • Lobosporangium transversale NRRL 3116 v1.0
Annotations/GenomesBacci1Coere1Gloin1Lichy1Linpe1Lobtra1Marpt1Morel2Mucci2Phybl2Rambr1Rhimi1_1Rhimi_ATCC11559_1Umbra1TotalAnnotation Description
Merops
4222043073112722942554053042843692532382724,190
3141225417636242812202022261Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1315Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
10143351544143351Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
4020313529291625352922293024394Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6445365767864273Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
16231215323322247Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111218Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112112210Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2221112111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
9457573876377684Families of peptidase inhibitors not assigned to clans
112
1111116
112
11
221128
11131111121115
513511121111124
11
1111141111111117Families of metallopeptidases not assigned to clans
2618201629202828231719181522299Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
3415224Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
345323261130Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4375535343444357Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
15871181071013129141111146Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1610121717171213111522111117201Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11587766712976510106Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111112111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
7343434365665261Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
314122232531137113126Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3518272021192120231720171918295Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4465564633832362Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
516Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11114Serine or threonine nucleophile; N-terminal nucleophile
224171541741910194311810203Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9649788261726695675562465271952Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12391811811155Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
7574356554765372Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
33Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2111111133111220Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11136342477465467Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111115Families of peptidases of unknown catalytic mechanism not assigned to clans
2111111111111115
2614172315181570242616242017325
12111118
1113
123