Peptidases • Syncephalastrum racemosum NRRL 2496 v1.0
Annotations/GenomesBacci1Lichy1Mucci2Phybl2Rhich1Rhimi1_1Rhimi_ATCC11559_1Rhimi_ATCC52814_1Rhior3Synrac1Umbra1TotalAnnotation Description
Merops
4223113042843762532382322902832723,265
3125242835202020332022278Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
10344543444348Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
4035352945293028283124354Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6567864646260Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1612332212234Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
12111129Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2212211121116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
977612777136687Families of peptidase inhibitors not assigned to clans
11
112116
112
11
21227
1111221123116
5321111124122
111121111111Families of metallopeptidases not assigned to clans
2616231728181515181522213Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
3411110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4543844444347Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1511131216141112131111139Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1617111514111110161417152Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1171295654481081Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
112121111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
73651065663259Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
3211211111317Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3520231731171919322018251Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4533532232335Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
22151019151188181110147Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9682675570465248537671716Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1312111111Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
7454765523351Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
314Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2133111211218Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11677965447470Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2111117Families of peptidases of unknown catalytic mechanism not assigned to clans
211121111112
2623242624242017232317247
11114
11
11