Peptidases • Mycotypha africana NRRL 2978 v1.0
Annotations/GenomesBacci1Mucci2Mycafr1Parpar1Rhimi1_1Thaele1Umbra1TotalAnnotation Description
Merops
4223042332652532942722,043
31241619202322155Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1043344331Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
40352330293424215Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
666566237Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1622224230Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111127Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
21111219Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
973777646Families of peptidase inhibitors not assigned to clans
111115
112
11
123
1112117
522312116
11111117Families of metallopeptidases not assigned to clans
26231520182622150Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
31116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
444444327Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1513121214121189Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
161191011101784Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
111277671060Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1211128Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
764566236Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
312312315Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
35231921172018153Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
433334323Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
221081111111083Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
96674961466771457Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
755767340Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
33Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
232111212Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1176465443Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
21111118
26242520242017156
11
11
11
11