Circinella umbellata NRRL1351 v1.0
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Annotations/GenomesAbsrep1Bacci1Blatri1Chlpad1Cirumb1Fenlin1Gonbut1Kircor1Liccor1Lichy1Mucci2Mycafr1Parpar1Phaart1Phybl2Rhich1Rhimi1_1Rhior3Synrac1Thaele1Zycmex1Zyghet1TotalAnnotation Description
Merops
3424222513163273372673673053113042332653232843762532902832943343026,786
26311823233424362625241619242835203320232431563Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
4103422346343324544444486Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
35402633283228363235352330312945292831343431705Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6656654645665678646655123Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
216313213112223332241259Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111111122111111111122Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2111212111221212225Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
993876698773766127136787161Families of peptidase inhibitors not assigned to clans
112
11111211110
111115
12332132118
81110
21222121111121222311132
352244253322341112424463
1111111111111121111121Families of metallopeptidases not assigned to clans
17262317172012191616231520161728181815261824421Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
133141215Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
444344344544453844444693Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1515111211141012911131212121216141311121212271Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
171671417151315191711910201514111614102412316Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1311595688771277695648756161Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111131121111211121228Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
77445527336455510663655113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
53252213212321211123145Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
33351830251922362020231921211731173220202425528Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4442222103533333533242476Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111111118Serine or threonine nucleophile; N-terminal nucleophile
1222151928251012141510811191915111811111814337Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
859650759393749277826749618655704653766794691,610Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
113331431115214135Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4743554574557447623748110Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
314Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
22212111132133111112133Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
91116598876764979647565145Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
23121110Families of peptidases of unknown catalytic mechanism not assigned to clans
21262220211915242023242520192624242323202115475
12121113211111121111127
11
1112311111
11
112