Spinellus fusiger NRRL 22323 v1.0
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Annotations/GenomesChlpad1Parpar1Phaart1Phybl2Radspe1Rhimi1_1Spifus1Zyghet1TotalAnnotation Description
Merops
3162653232842642532293022,236
2319242819201931183Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
4324343427Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
3330312931292331237Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6567565545Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1233122216Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
112112210Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
8766674751Families of peptidase inhibitors not assigned to clans
112
1113
11114
2316
2121221112
2341311419
111111118Families of metallopeptidases not assigned to clans
1720161717181424143Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
3115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
3453343631Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
121212121214121298Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1410201510111112103Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
9769566654Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111129Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
4555465539Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
5321211116Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3021211719171925169Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2333232422Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
191119191511914117Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7561865559465069501Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
151119Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3744463839Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1133111112Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
6497566548Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3115Families of peptidases of unknown catalytic mechanism not assigned to clans
2020192627242015171
21111118
112
11