Peptidases • Suillus pictus EM44 v1.0
Annotations/GenomesBoled1Paxru2Rhisa1Rhivi1Sclci1SerlaS7_9_2Suiame1Suibr2Suidec1Suigr1Suihi1Suilu3Suipic1TotalAnnotation Description
Merops
5052724974222863463425125983714004276715,649
61386264396149602545373493541,217Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
121221111122118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
20121916122215141716141319209Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
104106441076787790Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
432212111211223Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
54155Water nucleophile; water bound by Gln and Glu; all endopeptidases
1122232222232237Families of peptidase inhibitors not assigned to clans
1111217
123
222321222221225
222232222222227Families of metallopeptidases not assigned to clans
24123112191111121312121113193Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
21111111211114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
123Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
11811988118771089115Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16181618171516161814161617213Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1491813181513181513141316189Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111111113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
21115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
555566655585672Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111111111110Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
1411221113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19212121212121212319222022272Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5365245546561268Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Serine or threonine nucleophile; N-terminal nucleophile
126138691081088714119Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9071861077111410194967997841211,211Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
65214315211334Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
435843354464457Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
112111111111114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
422345433433343Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111214
1213816910633225021810310886166321,252
112
112