Peptidases • Syncephalis plumigaleata NRRL S24 v1.0
Annotations/GenomesBasme2finSCCoere1Conco1Linpe1Marpt1Rambr1Synplu1TotalAnnotation Description
Merops
5362044392722553692852,360
18424612349Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11316Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
311311313Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
33202229162217159Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
645358637Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
721253424Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111217Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
22Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
1547533340Families of peptidase inhibitors not assigned to clans
11
516
33
213
33
11
31116
21151111
2111117Families of metallopeptidases not assigned to clans
53182929281935211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
73015456Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
841336126Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
532554327Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
11888791364Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
33104017122211145Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
3055767666Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
434446429Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
2214752325378204Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
36182421212019159Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1042548538Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11114Serine or threonine nucleophile; N-terminal nucleophile
73446444346220Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
91499061666257476Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
231823Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
6510367441Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11211118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
515324727Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
21111118
28141715151613118
1214
112
279