Peptidases • Syncephalis fuscata S228 v1.0
Annotations/GenomesCoere1Conco1Conth1Marpt1Rambr1Synfus1Synplu1TotalAnnotation Description
Merops
2044393502553693252852,227
4226123332Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1214Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
111114312Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
20221716222217136Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
456586640Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
211531417Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1112117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
213Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
476334330Families of peptidase inhibitors not assigned to clans
11
11
213
11
12115
111115
1111116Families of metallopeptidases not assigned to clans
18291828193835185Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
3011157467Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
411361117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
323542322Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
8877971359Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10402512221911139Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
559675643Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
345465431Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
1475552537138227Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
18241921202319144Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4213485541Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
446294436746239Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
49906966625757450Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
341825Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5106675443Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
12111219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
156245730Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11111117
14172015161613111
2114
11
112
279