| function |
| 3677 Interacting selectively with DNA (deoxyribonucleic acid). | IPR012308 DNA ligase, ATP-dependent, N-terminal | | | 3909 Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+. | IPR016059 DNA ligase, ATP-dependent, conserved site | | | 3910 Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m). | IPR012310 DNA ligase, ATP-dependent, central | | | | IPR012309 DNA ligase, ATP-dependent, C-terminal | | | | IPR012308 DNA ligase, ATP-dependent, N-terminal | | | | IPR000977 DNA ligase, ATP-dependent | | | | IPR012308 DNA ligase, ATP-dependent, N-terminal | | | | IPR012310 DNA ligase, ATP-dependent, central | | | 5524 Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | IPR012310 DNA ligase, ATP-dependent, central | | | | IPR000977 DNA ligase, ATP-dependent | | | | IPR012310 DNA ligase, ATP-dependent, central | |
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| process |
| 51103 The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, as occurs during DNA repair. | IPR016059 DNA ligase, ATP-dependent, conserved site | | | 6281 The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | IPR012309 DNA ligase, ATP-dependent, C-terminal | | | | IPR012310 DNA ligase, ATP-dependent, central | | | | IPR012308 DNA ligase, ATP-dependent, N-terminal | | | | IPR000977 DNA ligase, ATP-dependent | | | | IPR012308 DNA ligase, ATP-dependent, N-terminal | | | | IPR012310 DNA ligase, ATP-dependent, central | | | 6310 The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. | IPR000977 DNA ligase, ATP-dependent | | | | IPR012308 DNA ligase, ATP-dependent, N-terminal | | | | IPR012309 DNA ligase, ATP-dependent, C-terminal | | | | IPR012310 DNA ligase, ATP-dependent, central | |
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