Gloeophyllum trabeum v1.0
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Gloeophyllum trabeum from James Lindsey

This genome was sequenced as a part of the large-scale multi-genome JGI CSP Saprotrophic Agaricomycotina Project (SAP), which focuses on the diversity and evolution of decay mechanisms, organismal phylogenetic relationships, and developmental evolution. A large collaborative effort led by PI of this project, David Hibbett (Clark University) aims for master publication(s) of the SAP data analysis. Researchers who wish to publish analyses using data from unpublished SAP genomes are respectfully required to contact the PI and JGI to avoid potential conflicts on data use and coordinate other publications with the SAP master paper(s).

Gloeophyllum trabeum is a brown rot fungus that has long been considered to belong to the Polyporales, but is now recognized as a member of the recently established order Gloeophyllales. Brown rot fungi have evolved multiple times independently in several lineages of the Basidiomycota, one origin is found in the Gloeophyllales. This small order of Agaricomycetes contains members displaying a high diversity in fruiting body forms. The ability of brown rotters to depolymerize cellulose and hemicellulose without removing the lignin barrier is considered a useful trait for improving the feedstock quality in biofuel production. Initial reports indicate that hydroxyl radical generation via a hydroquinone driven Fenton chemistry and secretion of low-molecular weight peptides are part of the mechanism employed by G. trabeum. The whole genome sequence of G. trabeum will be the first to represent the Gloeophyllales. It would be particularly informative to compare the genome of G. trabeum with two other sequenced brown rot species, Postia placenta and Serpula lacrymans, to elucidate the mechanisms of brown rot decay as each of them represents an independent branch of brown rot fungi. Thus, the genome of G. trabeum is expected to further research efforts in support of the DOE mission to strengthen innovative approaches in the quest for sustainable and affordable biofuel production.

Genome Reference(s)

References

Binder M, DS Hibbett, K-H Larsson, E Larsson, E Langer and G Langer. 2005. The phylogenetic distribution of resupinate forms across the major clades of mushroom-forming fungi (Homobasidiomycetes). Syst Biodivers 3:113-157.

Hibbett DS et al. 2007. A higher-level phylogenetic classification of the Fungi. Mycol Res 111:509-547.

Kerem Z, KA Jensen, and KE Hammel. 1999. Biodegradative mechanism of the brown rot basidiomycete Gloeophyllum trabeum: evidence for an extracellular hydroquinone-driven fenton reaction. FEBS Letters 446:49-54.

Wang W and PJ Gao. 2003. Function and mechanism of a low-molecular-weight peptide produced by Gloeophyllum trabeum in biodegradation of cellulose. J Biotechnol 101:119-130.