Fusarium redolens A4 v1.0
Image Credit: Stephane Hacquard
Fusarium redolens growing in the lab.
Image Credit: Stephane Hacquard

This genome was sequenced as part of the 1000 Fungal Genomes Project - Deep Sequencing of Ecologically-relevant Dikarya, and more specifically as part of the Endophyte Genome Sequencing project, which seeks to sequence members of diverse lineages of endophytic species found in Arabidopsis, Populus and other plants to examine the functional diversity of fungi with a shared evolutionary history.

Fusarium redolens isolates (Ascomycota phylum; Sordariomycetes class; Hypocreales order) have been primarily described as plant pathogens, causing root rot disease. However, several isolates were also isolated from asymptomatic plants and therefore live benignly within host tissues, as endophytes. Particularly, their bioactive potential and biological roles for plant protection have been underlined. Notably, the cyclic hexadepsipeptide mycotoxin Beauvericin, which has strong antibacterial, antifungal and insecticidal activities has been purified from the mycelium of Fusarium redolens Dzf2. The sequenced Fusarium redolens A41 isolate has been isolated from healthy Arabidopsis thaliana plants grown in natural soil after surface sterilization of plant roots. The sequencing of this fungal isolate is part of a larger project aiming at sequencing the genomes of numerous phylogenetically diverse root-associated fungi from Arabidopsis, Populus, and other plant hosts for further comparative genome analysis. Unravelling the genomic signatures reflecting the adaptation of these microbes to the host cell environment represent a promising way to better understand how the endophytic lifestyle evolved in phylogenetically unrelated fungal species. Comparative genome analysis between different plant hosts, and between saprotrophic, mycorrhizal, and pathogenic fungi will provide new insights into the specific adaptations but also the conserved signatures associated with these different lifestyles. Genome mining will also provide relevant information regarding its bioactive potential.

Researchers who wish to publish analyses using data from unpublished CSP genomes are respectfully required to contact the PI and JGI to avoid potential conflicts on data use and coordinate other publications with the CSP master paper(s).


1Note that the strain ID is based on the closest NCBI hit. We need to validate the phylogeny using whole genome sequencing data and attribute a novel strain ID.